Prevalence of Chronic Rhinosinusitis in Cystic Fibrosis

Completed

• Conditions: Sinusitis; Cystic Fibrosis
• Interventions: Other: Assessment of upper and lower airway colonization, sinonasal symptoms, history, rhinoscopy and rhinomanometry.

• Registration Number: NCT00266474
• Lead Sponsor: University of Jena

Brief Summary

Aim of the study is to detect the prevalence of chronic rhinosinusitis and the colonisation with Pseudomonas aerug. in the upper airways in patients with cystic fibrosis.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-12
• Study First Submitted: 2005-12-15
• Study First Submitted QC: 2005-12-15
• Study First Posted: 2005-12-16
• Study Completion: 2007-09
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-03
• Last Update Posted: 2014-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 187

Inclusion Criteria

• Subject has a confirmed diagnosis of cystic fibrosis

Exclusion Criteria

• current systemic therapy against Pseudomonas aeruginosa

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cross sectional CF study	Assessment of upper and lower airway colonization, sinonasal symptoms, history, rhinoscopy and rhinomanometry.	Multicentric study, including 187 CF patients of all age groupr in 5 CF centres.

Primary Outcome Measures

Name	Time	Method
Pathogen colonization in upper and lower airways	3yrs
Sinonasal symptoms (SNOT-20)	3 yrs
rhinomanometry and rhinoscopy	3yrs

Trial Locations

Locations (1)

Friedrich-Schiller-Universität; 🇩🇪 Jena, Thüringen, Germany