A pilot study comparing the efficacy of artesunate alone and artesunate plus azithromycin for the treatment of Plasmodium falciparum malaria in central Vietnam

Phase 2

Recruiting

• Conditions: Malaria infection; Infection - Other infectious diseases

• Registration Number: ACTRN12610000546055
• Lead Sponsor: Australian Army Malaria Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-07-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

(i) Patients with falciparum malaria with parasitaemia between 100 and 200,000 parasites/uL of blood
(ii) Is willing to give small amounts of blood via finger prick and phlebotomy
(iii) Written informed consent and agreed to treatment follow-up for a total of 28 days for artesunate alone and 42 days for artesunate plus azithromycin.

Exclusion Criteria

(i) Severe/cerebral malaria or history of another serious medical disease
(ii) Prior treatment with an artemisinin drug within the previous 7 days
(iii) Pregnancy and lactating
(iv) Inability to communicate well with the investigator (poor mental development or evidence of psychiatric disorder)

Study & Design

• Study Type: Interventional
• Study Design: Not specified