A Randomised Controlled Trial to find out the optimal maintenance fluid in children with very severe pneumonia
Not Applicable
- Conditions
- Health Condition 1: null- Children with very severe pneumonia
- Registration Number
- CTRI/2013/02/003398
- Lead Sponsor
- ady Hardinge Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 112
Inclusion Criteria
Fever with cough with fast breathing and chest indrawing with nasal flaring or grunting plus at least one of the following
Central cyanosis
Inability to breastfeed or drink or vomiting everything
Convulsions lethargy or Unconsciousness
Severe respiratory distress
Exclusion Criteria
Meningitis
Encephalitis
Congestive cardiac failure
Known Renal disease
Chronic Liver Disease
Shock at presentation
Severe acute malnutrition
Known endocrinal disease
Refusal of consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients developing hyponatremia that is serum sodium less than 135 mmol per litre after receiving intravenous maintenance fluids.Timepoint: At 6 hours <br/ ><br>At 12 hours <br/ ><br>At 24 hours
- Secondary Outcome Measures
Name Time Method Proportion of patients developing clinically symptomatic hyponatremia <br/ ><br>Timepoint: At 6 hours <br/ ><br>At 12 hours <br/ ><br>At 24 hours;Proportions of patients developing hypernatremia that is serum sodium more than 150 mmol per litreTimepoint: At 6 hours <br/ ><br>At 12 hours <br/ ><br>At 24 hours