Proteom analysis in Serum of pediatric hemato-oncological patients with invasive aspergillosis
- Conditions
- B44.7Disseminated aspergillosis
- Registration Number
- DRKS00031416
- Lead Sponsor
- Institut für medizinische Mikrobiologie und Hygiene, Universitätsklinikum Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
hematooncologic primary disease
retained serumsamples with detection of galactomannan
informed consent given
Exclusion Criteria
other kind of immunosuppression
therapy with PLASMA-LYTE™ in a timeframe of four weeks to when the serumsample was taken
no retained serum samples available
no informed consent given
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proteomanalysis of retained serum-samples of the patient collctive at timepoints before and at the time of galactomannan-detection as well as serum-samples of the controll-collektives by mass-spectrometry.
- Secondary Outcome Measures
Name Time Method Analysis of serumprotein-expressionlevels and clinical data for identification of potential biomarkers of invasive aspergillosis.