Effect of woodsmoke on the respiratory health of adults with and without chronic respiratory diseases

Completed

• Conditions: Stress ten gevolge van houtrook; acute stress; asthma; COPD; 10024967

• Registration Number: NL-OMON49800
• Lead Sponsor: niversiteit Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Participant is 30 years or older
Participant lives in the participating study area
Participants for the asthma/COPD panel need to comply with the following
criteria:
o Self-reported doctors diagnosis of asthma/COPD.
o Report of wheezing, shortness of breath And/or use of asthma/COPD medication
in the past 12 months.
Participants for the healthy adult panel need to comply with the following
criteria:
o No self-report of a doctor diagnosis of asthma/COPD ever
o No report of wheezing, shortness of breath, chronic cough, phlegm in the past
12 months
o No use of asthma/COPD medication in the past 12 months

Exclusion Criteria

Active smokers
Subjects with a wood stove or fireplace
People with absolute contra-indications for spirometry:
o Heart attack in the last three months
o Chest or abdominal surgery in the past 3 months
o A brain, ear or eye surgery in the past 1 month

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study endpoints are lung function (FEV1 and PEF), daily respiratory<br /><br>symptoms, use of bronchodilator medication, and cortisol. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary parameters include inflammatory markers Interleukin (IL) 1b, IL-6,<br /><br>IL-8, IL-10, and tumour necrosis factor (TNF)*. </p><br>