Peripheral Metabolic Effects of Ghrelin

Phase 1

Completed

• Conditions: Healthy Controls
• Interventions: Drug: Ghrelin

• Registration Number: NCT00771940
• Lead Sponsor: University of Aarhus

Brief Summary

The aim of this study is to investigate putative peripheral effects of ghrelin on glucose and lipid metabolism in healthy men. Eight subjects will be enrolled. The hypothesis is that ghrelin infusion causes insulin resistance and lipolysis.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-10
• Study First Submitted: 2008-10-08
• Study First Submitted QC: 2008-10-13
• Study First Posted: 2008-10-15
• Primary Completion: 2009-01
• Study Completion: 2009-01
• Status Verified: 2009-02
• Last Update Submitted: 2009-02-02
• Last Update Posted: 2009-02-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 8

Inclusion Criteria

1. BMI < 27 kg/m2
2. Written informed consent
3. Non-smoker

Exclusion Criteria

1. Any disease including epilepsy
2. Any use of medications (excl. paracetamol)
3. Present or previous malignancy
4. Alcohol dependency
5. Allergy to any trial medication

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Ghrelin	Ghrelin	-

Primary Outcome Measures

Name	Time	Method
Plasma levels of glucose	During study day

Secondary Outcome Measures

Name	Time	Method
Insulin signaling	Study day
Serum levels of fatty acids	Study day

Trial Locations

Locations (1)

Aarhus University Hospital; 🇩🇰 Aarhus, Denmark