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Clinical Trials/NCT02564640
NCT02564640
Completed
Not Applicable

Comparison of Hemodynamic Changes After Endotracheal Intubation by Using the Videolaryngoscope and the Macintosh Direct Laryngoscope in Elderly Hypertensive Patients

Antalya Training and Research Hospital1 site in 1 country100 target enrollmentJune 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anesthesia Intubation Complication
Sponsor
Antalya Training and Research Hospital
Enrollment
100
Locations
1
Primary Endpoint
Blood pressure changes during tracheal intubation ( mmHg ) ,
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Tracheal intubation techniques that avoid or minimize pharyngolaryngeal stimulation might attenuate the hemodynamic stress response. Tracheal intubation using video laryngoscope needs comparatively less airway manipulation so, the investigators expect less hemodynamic response while using videolaryngoscope.

Detailed Description

The hemodynamic stress response to tracheal intubation can precipitate adverse cardiovascular events in patients with cardiovascular disease. Which is shown to greatly increase the risk of myocardial infarction or stroke, especially in elderly patients with hypertension. Direct laryngoscopy and laryngoscopic stimulation of pharyngolaryngeal structures may be an important factor in the hemodynamic stress response associated with tracheal intubation. Patients were randomly allocated to two groups using a permuted block randomization method: 1) patients intubated by using the videolaryngoscopy 2) patients intubated by using the Macintosh laryngoscope . SAP, MAP, and heart rate were measured and recorded in the operating room: At baseline, before intubation, immediately after intubation and 1,2,3,4 and 5 minutes after tracheal intubation.

Registry
clinicaltrials.gov
Start Date
June 2015
End Date
September 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Antalya Training and Research Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • American Society of Anesthesiologists Physical Status II-III,
  • aged over 65 years,
  • controlled hypertensive patients,
  • scheduled for elective coronary artery bypass grafting.

Exclusion Criteria

  • American Society of Anesthesiologists Physical Status IV,
  • ejection fraction \< 40%,
  • any anatomical abnormality in head, neck or face,
  • Mallampati score of IV,
  • history of difficult intubation or laryngoscopy

Outcomes

Primary Outcomes

Blood pressure changes during tracheal intubation ( mmHg ) ,

Time Frame: At baseline, 1 minute before intubation, and 1,2,3,4 and 5 minutes after tracheal intubation

Secondary Outcomes

  • ST segment elevation in electrocardiogram indicating myocardial ischaemia during tracheal intubation(At baseline, 1 and 5 minutes after tracheal intubation.)
  • Arrhythmic changes in electrocardiogram during tracheal intubation(At baseline, 1 and 5 minutes after tracheal intubation.)
  • Heart rate changes during tracheal intubation (beats per minute)(At baseline, 1 minute before intubation, and 1,2,3,4 and 5 minutes after tracheal intubation)

Study Sites (1)

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