Propofol versus Ketofol in Endoscopic retrograde cholangiopancreatography ERCP BIS guided sedatio
Phase 2
- Conditions
- Anaesthesia
- Registration Number
- PACTR201907799024111
- Lead Sponsor
- ational liver institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
•Adult patients aged 18 to 60 years undergoing ERCP
•American Society of Anesthesiologists physical status class I-II.
Exclusion Criteria
•Patients with severe cardiovascular disease.
•History of bronchial asthma.
•Drug allergy to propofol or ketamine.
•History of long term uptake of narcotics, benzodiazepine or any neuropsychiatric medication.
•Pregnancy.
•Obese patient with body mass index more than 36.
•History of any neurological insult.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method •Primary aim of the study was to compare propofol and ketofol as a sedative agent regards induction time and recovery time in adult patients undergoing ERCP.
- Secondary Outcome Measures
Name Time Method •Secondary aim was to investigate the safety and efficacy of both drugs as regards haemodynamic, respiratory compromise, pain, nausea, vomiting, any psychomimetic effect (Agitation, Irritability…) post procedure patient and endoscopiest satisfaction as well as the total dose of drug consumption.