The study of effect on the electrical impulses generated by brain when either two of the anaesthetic drugs (propofol or ketofol) is used to maintain anaesthesia in patients who are undergoing surgery for cerebello pontine angle tumours
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anaesthesiologists Class I or II patients
Adult Patients with BMI less than 30
Exclusion Criteria
Patients unable (legally incompetent) or unwilling to give consent.
Previous history of psychiatric, anxiety or post-traumatic stress disorders.
History of allergy to study drugs.
Patient on sedative or hypnotic medication.
Patients with chronic pain or on painkiller.
Patients with severe hepatic or kidney disorders.
Patients having a history of thyrotoxicosis or cardiac disorders.
Patients on chronic beta blockers.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Compare the effect of Propofol and Ketofol on amplitude and latency of Transcranial Motor Evoked Potentials when these agents are used with Fentanyl for the maintenance of general anaesthesia in cerebellopontine angle tumour surgeriesTimepoint: Amplitude and latency to be recorded every 30 minutes for the first 3 hours of surgery followed by every hour till the end of surgery
- Secondary Outcome Measures
Name Time Method 1.Comparison of hemodynamic intraoperative parameters between the two anaesthetic regimens every 30 minutes for the first 2 hours then every hour till the end of surgery. <br/ ><br> <br/ ><br>2.Complications like nausea vomiting, pain at injection site, nystagmus, agitation, hallucinations etc <br/ ><br>Timepoint: 1. Every 30 minutes for the first 3 hours of surgery followed by hourly till the end of the surgery <br/ ><br>2. After extubation of the patients which is usually 12 hours after surgery