To compare effects of Propofol and Ketofol on Heart rate, Blood pressure, Mean Arterial pressure, SpO2 and Rate pressure product in Patients Undergoing Laparoscopic Cholecystectomy Under General Anaesthesia
Phase 1
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/10/058294
- Lead Sponsor
- Dr Shobha Purohit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients willing to give written informed consent.
2.Patients undergoing Laparoscopic surgery under General Anaesthesia.
3.ASA Grade I & II.
4. Age Groups-18-55 years.
Exclusion Criteria
1.Patients with history of drug allergy, egg allergy.
2.Patients with uncontrolled hypertension and diabetes mellitus.
3.Patients with history of psychiatric illness.
4.Pregnant patients
5.Patients with BMI >30kg/m2
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Mean Heart Rate , <br/ ><br>2.Mean Systolic Blood Pressure, <br/ ><br>3.Mean Diastolic Blood Pressure, <br/ ><br>4.Mean Arterial Pressure, <br/ ><br>5.Mean SpO2, <br/ ><br>6.Mean Rate Pressure Product,Timepoint: Baseline <br/ ><br>After Induction of Anaesthesia <br/ ><br>Immediately after Intubation (T0) <br/ ><br>1 min after Intubation (T1 ) <br/ ><br>3 min after Intubation (T3) <br/ ><br>5 min after Intubation (T5 ) <br/ ><br>10 min after Intubation (T10) <br/ ><br>15 min after Intubation (T15) <br/ ><br>Just before pneumoperitoneum created1.Mean Heart Rate , <br/ ><br>2.Mean Systolic Blood Pressure, <br/ ><br>3.Mean Diastolic Blood Pressure, <br/ ><br>4.Mean Arterial Pressure, <br/ ><br>5.Mean SpO2, <br/ ><br>6.Mean Rate Pressure Product,
- Secondary Outcome Measures
Name Time Method Proportion of cases who will experience side effects.SHIVERING GRADE <br/ ><br>HYPOTENSION HYPERTENSION <br/ ><br>BRADYCARDIA TACHYCARDIA <br/ ><br>RESPIRATORY DEPRESSION <br/ ><br>PONV GRADE <br/ ><br>HALLUCINATION NYSTAGMUS DELIRIUMTimepoint: 15 MIN,30 MIN,45 MIN,60 MIN,75 MIN,90 MIN,105 MIN,120 MI