A Trial of Polyethylene Glycol (PEG) Hydrogel to Reduce Rectal Radiation Dose During Radiotherapy for Prostate Cancer

Phase 1

• Conditions: Rectal toxicity during prostate radiotherapy (brachytherapy and/or external beam radiotherapy); Cancer - Prostate

• Registration Number: ACTRN12612000524897
• Lead Sponsor: St George Hospital Cancer Care Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-05-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

Histopathologically confirmed, localised prostate cancer, fit for prostate brachytherapy or dose escalated external beam radiotherapy with iducial marker localisation, fit for general anaesthetic. No prior history of bleeding disorder, prior transurethral resection of the prostate (TURP), transurethral incision of the prostate (TUIP), bladder neck resection, perirectal/perianal abscess, rectal/anal fissure. No prior history of prostate or pelvic radiotherapy. Able to provide written informed consent.

Exclusion Criteria

Previous history of bleeding disorder, prior TURP, TUIP, bladder neck resection, perirectal/perianal abscess, rectal/anal fissure. Prior history of prostate or pelvic radiotherapy. Unfit for general anaesthetic. Unable to provide written informed consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified