Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision
- Registration Number
- NCT00575354
- Lead Sponsor
- Nanjing Medical University
- Brief Summary
Generally, benign breast tumors are excised under the local anesthesia. But such action was so invasive that every patient would experience the physiological and psychological stimuli unavoidably. Sevoflurane was advised as a better inhalational anesthesic for its "easy come,easy go" property during short-lasting operations than isoflurane. We purposed that sevoflurane would be a superior anesthesic for benign breast tumor excision than isoflurane with relative less alteration in hemodynamics, less postoperative side effects and easily-control the depth of anesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 500
Inclusion Criteria
- Chinese
- Diagnosed benign breast tumor patients
- 18-64 yrs
Exclusion Criteria
- Allergic to any interventional drugs
- Organic dysfunction
- Long-lasting PACU staying
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 Sevoflurane Sevoflurane: induction 3-6%, maintenance 2-3% 2 Isoflurane Isoflurane: induction 3-6%, maintenance 2-3%
- Primary Outcome Measures
Name Time Method Time of induction, maintenance and resuscitation 0h to the end of the operation
- Secondary Outcome Measures
Name Time Method Intraoperative hemodynamics; Postoperative side effects; 0h to 24h after the end of the operation
Trial Locations
- Locations (1)
Nanjing Maternal and Child Care Hospital
🇨🇳Nanjing, Jiangsu, China