Perisurgical observation of nociceptive thresholds during total knee arthroplasty for association with persisting postsurgical pain: an explorative study
- Conditions
- Total knee arthroplasty, persisting pain, chronic pain
- Registration Number
- NL-OMON26714
- Lead Sponsor
- Radboudumc
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Patients scheduled for total knee arthroplasty.
Exclusion Criteria
- Patient’s refusal
- Preexisting neurological or psychiatric illnesses
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Persistent postsurgical pain (PPSP)<br /><br>- eQST<br /><br> o Electrical pain threshold (ePT) [mA]<br /><br> o Electrical pain tolerance threshold (ePTT) [mA]<br /><br>- Nociceptive Perception thresholds (NPT)<br /><br> o Stimulus amplitude [mA]<br /><br> o Responses to stimuli (perceived/not perceived)<br /><br> o Stimulation time [s]<br />
- Secondary Outcome Measures
Name Time Method - Pain intensity (NRS)<br /><br>- McMaster Universities Osteoarthritis Index (WOMAC)<br /><br> o Pain scale<br /><br> o Stiffness scale<br /><br> o Functional scale<br /><br>- Knee Society Score (KSS)<br /><br> o Functional scale<br />