Reduction in bleeding in middle ear surgeries with target control infusion with propofol, and comparison with dexmedetomidine and fentanyl fixed dose
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/02/049466
- Lead Sponsor
- Vijayanagar institute of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.All patients undergoing middle year surgeries of 18-60 years of age.
2.American society of anaesthesiologists physical status I and II
3. Non obese (BMI- 18.5-29.9)
Exclusion Criteria
1.Refusal of patients consent
2.Patients with significant systemic disease
3.Patients on long term and concurrent sedative intake
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in surgical bleedingTimepoint: Reduction in surgical bleeding 1) post intubation (every 5 min) <br/ ><br>2) following 24 hours after surgery
- Secondary Outcome Measures
Name Time Method changes in systolic BP, diastolic BP, mean BP, heart rate, SP02, EtCO2. <br/ ><br>Total propofol used. <br/ ><br>Correlation of TCI propofol with the state entropy levels. <br/ ><br>Incidence of postoperative nausea and vomiting. <br/ ><br>Timepoint: pre induction <br/ ><br>intubation <br/ ><br>post intubation <br/ ><br>every 5 min intraoperative