Analysis of the Variation of the Retinal Vascularization After a Prolonged Effort
- Conditions
- Retinal Vascular DisorderSport Injury
- Registration Number
- NCT03864380
- Lead Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
- Brief Summary
The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization.
The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition.
The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise.
This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date.
The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized.
the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 29
- Person registered at the 2019 Paris Marathon
- Ophthalmological disorders making access to the fundus impossible for both eyes
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Density of retinal vascular plexuses up to 1 hour Percentage, Measurement with OCT-A
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Fondation A de Rothschild
🇫🇷Paris, France
Fondation A de Rothschild🇫🇷Paris, France