Modulation of deep cortical regions by means of low intensity transcranial focused ultrasound (tFUS) neuromodulatio

Withdrawn

• Conditions: The experiment is conducted on healthy participants. Using the proposed technique we aim at understanding the neural substrate of empathy; emotions; empathy

• Registration Number: NL-OMON49840
• Lead Sponsor: etherlands Institute for Neuroscience

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

healthy participants, age 18-35

Exclusion Criteria

A potential subject who does not meet any of the following criteria will be
excluded from participation in this study:

- Proficiency with the English language
- Potential participants will be asked to fill a standard questionnaire for
neuromodulation studies (TMS/tDCS) to exclude any participant with
contraindications to brain stimulation/neuromodulation.

* EXAMPLE OF SAFETY SCREENING
* Have you ever:
Had an adverse reaction to neuromodulation or ultrasound?
Had a seizure?
Had an EEG?
Had a stroke?
Had a head injury (include neurosurgery)?
* Do you have any metal in your head (outside of the mouth,) such as shrapnel,
surgical clips, or fragments from welding or metalwork?
* Do you have any implanted devices such as cardiac pacemakers, medical pumps,
or intracardiac lines, cochlear implants, implanted brain stimulators,
implanted defibrillator?
* Do you suffer from frequent or severe headaches?
* Have you ever had any other brain-related condition?
* Have you ever had any illness that caused brain injury?
* Are you taking any medications? (e.g. Tricyclic anti-depressants, neuroleptic
agents, and other drugs that lower the seizure threshold)
* If you are a woman of childbearing age, are you sexually active, and if so,
are you using a reliable method of birth control?
* Does anyone in your family have epilepsy?
* Do you need further explanation of the technique and its associated risks?

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcome of the study will be participant performance in our task.<br /><br>(Behavioural Outcome)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>-</p><br>