tility of ultrasound scan as a predictor of life threatening bleeding in patients with liver disease
- Conditions
- Health Condition 1: K740- Hepatic fibrosis
- Registration Number
- CTRI/2022/11/047479
- Lead Sponsor
- Father Muller Research Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Men and women aged between 30 to 65 years who are diagnosed to have chronic liver disease based on supporting history and laboratory parameters.
2.History of significant alcohol consumption as defined by more than 21 units and 14 units of alcohol per week for males and females respectively.
3.Time interval between SWE and OGD < 30 days
4.No history of consumption of beta blockers
5.No known prior liver insult â?? Infections, recreational drugs, autoimmunity, etc.
6.No previous history of upper gastrointestinal haemorrhage in the past
1.Non alcoholic causes of liver cirrhosis. (Viral, toxins, extra-hepatic porto-venous obstruction and childhood history of paediatric cirrhosis)
2.Patients with ultrasongraphy findings of fatty liver
3.Patients with significant alcohol consumption who have alcoholic liver diseases in the stage of steato-hepatitis.
4.Patient on treatment with hepatotoxic drugs for an unrelated condition
5.Prior diagnosis of portal hypertension, oesophageal varices, hepatocelluar carcinoma, hepatic encephalopathy, portal vein thrombosis and liver trauma
6.Concomitant comorbidities such as heart failure â?? NYHA III and IV, acute asthma attack, recent myocardial infarction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Aims to identify a cut off value which can accurately diagnose the presence of varices.Timepoint: 1 year
- Secondary Outcome Measures
Name Time Method not applicableTimepoint: not applicable