Pre- and post-surgical medical treatment of human cystic echinococcosis

Not Applicable

Completed

• Conditions: Cystic echinococcosis; Infections and Infestations

• Registration Number: ISRCTN78387420
• Lead Sponsor: niversity of the Republic

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-12-20
• Study Start: 2023-08-02
• Last Update Posted: 30 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Patients were recruited from January 2003 to October 2020 from different hospitals throughout Uruguay who completed the 5 years post-treatment follow-up in October 2020
2. Patients with cystic echinococcosis diagnosis, based on clinical symptoms, morphological features detected by imaging techniques (RX, US, CT, MR) and immunologic tests (indirect hemagglutination [IHA], indirect immunofluorescence [IFI])
3. Less or equal cysts size to 7 cm, remnants post-surgical act, high surgical risk or multiple locations
4. Stage CE1, CE2 o CE3a o CE3b

Exclusion Criteria

1. Patients who did not fulfil the follow-up criteria
2. Surgical treatment: Patients with low or moderate surgical risk and cysts larger than 7 cm, were subjected to surgery. However, the protocols require mandatory surgery for any cysts with a pulmonary location.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Size of the cyst measured by computed tomography (CT) or nuclear magnetic resonance (NMR) at 5 years of follow-up

Secondary Outcome Measures

Name	Time	Method
Stage of the cyst measured by computed tomography (CT) or magnetic resonance imaging (MRI) from active (CE1, CE2) to inactive (CE4 and CE5) stages during medical treatment at 5-year follow-up