The Influence of Sensory Phenotype on the Risk of Developing Neuropathic Pain

• Conditions: Peripheral Nerve Injury; Polyneuropathy; Neuropathic Pain

• Registration Number: NCT02666456
• Lead Sponsor: University of Kiel

Brief Summary

Cross-sectional and longitudinal analysis of the somatosensory phenotype, assessed by quantitative sensory testing (QST) and Information obtained by questionnaires to detect risk factors for neuropathic pain development and chronification in painless and chronic pain patients.

Detailed Description

Not available

Study Timeline

• Status Verified: 2016-01
• Study First Submitted: 2016-01-11
• Study First Submitted QC: 2016-01-25
• Last Update Submitted: 2016-01-25
• Study First Posted: 2016-01-28
• Last Update Posted: 2016-01-28
• Study Start: 2016-04
• Primary Completion: 2019-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• Chronic peripheral neuropathic pain or
• Painless Patient with risk to develop neuropathic pain (post-surgery, chemotherapy-induced)

Exclusion Criteria

• Minors

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Somatosensory phenotype detected by quantitative sensory testing (QST)	Single assessment at baseline (cross-sectional study). Report of complete cohort data at study completion	The somatosensory phenotype will be assessed by quantitative sensory testing (QST) once at baseline
Change of neuropathic pain: Development and chronification of neuropathic pain detected by DN4 questionnaire	Assessment of change of neuropathic pain from baseline and 6 months after study enrollment (longitudinal study). Report of complete cohort data at study completion.	Assessment with DN4 pain questionnaire