Effects of Neuromodulation associated with Treadmill gait Training on functional mobility and balance in people with Parkinson's Disease
- Conditions
- GaitC10.228.140.079.862.500
- Registration Number
- RBR-5r6pm9x
- Lead Sponsor
- niversidade Federal da Paraíba
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Men and women between 18 and 80 years old; people with Parkinson's Disease (PD) in Hoehn Yahr stages between 2 and 4 (moderate disease) whose primary symptom includes gait alteration; being able to walk independently for 30 meters or with a unilateral assistive device; having a Mini-Mental State Examination (MMSE) score greater than or equal to 24 for people with more than 8 years of schooling and above 20 points for illiterate people
Unstabilized psychiatric comorbidities; other neurological disorders, musculoskeletal, orthopedic, cardiovascular, and respiratory changes that may affect the ability to walk on the treadmill; labyrinthine problems; deep brain stimulation surgery or epidural stimulation of the spinal cord; uncontrolled infection or other uncontrolled pre-existing medical conditions (e.g. uncontrolled infection or other uncontrolled pre-existing medical conditions (e.g. decompensated diabetes, hypertension, symptomatic lung or heart disease); concomitant treatment with other experimental drugs; pregnant or breastfeeding women; chronic low back and lower limb pain; not walking without an aid (cane, crutch, walker) or help from another person; metal implants and cardiac pacemakers; history of neurosurgery
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We expected to find a change in gait speed between the pre-stimulation and post-stimulation conditions between the two groups, as assessed by the 10-meter walk test (fast speed), of at least 5%.
- Secondary Outcome Measures
Name Time Method We expected to find a change in functional mobility between the pre-stimulation and post-stimulation conditions between the two groups, as assessed by the Timed Up and Go Test, of at least 5%.;It is expected to find a change in dynamic balance performance between the pre-stimulation and post-stimulation conditions between the two groups assessed through the Mini-Balance Evaluation Systems Test (Mini-BESTest), of at least 5%.;We expected to find a change in the perception of quality of life between the pre-stimulation and post-stimulation conditions between the two groups, as assessed by the Parkinson's Disease Questionnaire (PDQ-39), of at least 5%.