Fluid responsiveness in renal transplant patients after tidal volume challenge test
Not Applicable
Completed
- Conditions
- Health Condition 1: N186- End stage renal disease
- Registration Number
- CTRI/2022/04/042038
- Lead Sponsor
- Mahatma Gandhi Hospital and Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 36
Inclusion Criteria
Patients of end-stage renal disease undergoing renal transplantation
-Age group of 18-60 years
-Patient with written informed consent
Exclusion Criteria
-Patient refusal
-Cadaveric donor renal transplantation
-Recurrent cardiac arrhythmia
-Reduced ventricular systolic function - left (ejection fraction <40%)
-BMI more than 30
-Intra-operative use of vasopressors or inotropes before or during VTC
-Chronic lung disease
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine efficacy of PPV and SVV changes after tidal volume challenge in predicting fluid responsiveness in a renal transplant recipient under general anaesthesia with lung protective ventilation.Timepoint: The tidal volume Challenge (TVC) test will be performed when patient develop hypotension (fall in Systolic Arterial Pressure 20 % from the baseline / MAP below 70 mm/Hg) prior to administration of fluid bolus or any vasopressor agents. Only the data obtained from the first fluid challenge administered to each enrolled patient will be used for the analysis.
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI