Efficacy of proton pump inhibitor for chronic cough caused by gastroesophageal reflux; double-blind, placebo-controlled, randomized clinical trial
Not Applicable
Recruiting
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0000543
- Lead Sponsor
- Yonsei University Health System, Gangnam Severance Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 132
Inclusion Criteria
chronic cough patient from 18 to 70 years
Exclusion Criteria
? less than 18 yrs, more than 70 yrs
? current smoker, ex-smoker within 3 months
? underlying lung disease
? Bronchial asthma patients
? postnasal drip patients
? Previously PPI failure patients
? Previously reflux surgery performed patients
? gastrointestinal malignancy or Barrett's esophagus
? Upper airway infection history within 8 weeks
? Currently taking PPI, H2-receptor antagonist, beta-blocker, ARB, steroid, anti-cholinergics
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method