Haloperidol versus Dexmedetomidine as an Adjuvant to Ondansetrone in Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy
Phase 1
- Conditions
- Anaesthesia
- Registration Number
- PACTR202311673887516
- Lead Sponsor
- Faculty Of Medicine Ain Shams University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 75
Inclusion Criteria
1.Age (18 – 65) undergoing laparoscopic cholecystectomy.
2.American Society of Anesthesiologist (ASA)- physical status I & II
3.No history of psychiatric illness
4.No Parkinson's disease, motion sickness or history of chemotherapy
5.Both gender
Exclusion Criteria
1.Patients on (steroids, antiemetics, or any drug that may cause emesis).
2.Pregnancy.
3.Any active cardiac or chest condition at the time of surgery
4.ASA = III and IV physical status
5.Parkinson's disease
6.Patients with psychiatric disease history
7.Patients on chemotherapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method •Incidence of PONV in the 1st postoperative 24 hours<br>
- Secondary Outcome Measures
Name Time Method <br>•The number of nausea and vomiting attacks.<br>•Severity of postoperative nausea and vomiting using a 10 cmVAS score rating scale.<br>•Use of rescue aniemetic<br>•Assessment of postoperative pain using VAS score<br>•The sedation scores (Observer’s Assessment of Alertness/Sedation (OAA/S) scale) (where 1 =awake/alert, 2=light sedation, 3=moderate sedation, 4=deep sedation and 5 = deep sleep)<br>