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Clinical Trials/ISRCTN82431978
ISRCTN82431978
Active, not recruiting
未知

HEmodynamic effects of Reducing left ventricular Afterload with impella or intra-aortic balloon CounterpuLsation during veno-arterial Extracorporeal membrane oxygenation in cardiogenic Shock (HERACLES)

King's College London0 sites36 target enrollmentJanuary 19, 2022
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Overview

Phase
未知
Intervention
Not specified
Conditions
Not specified
Sponsor
King's College London
Enrollment
36
Status
Active, not recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
January 19, 2022
End Date
November 28, 2026
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Patients aged \=18 years with cardiogenic shock of any aetiology
  • •2\. On veno\-arterial extracorporeal membrane oxygenation (VA\-ECMO) support or starting VA\-ECMO post PCI
  • •3\. Undergoing clinically indicated cardiac catheterisation

Exclusion Criteria

  • •1\. Post\-cardiotomy cardiogenic shock
  • •2\. Confirmed left ventricular thrombus on imaging
  • •3\. Age \<18 years
  • •4\. Pregnancy or peripartum cardiomyopathy
  • •5\. Contraindication to either intra\-aortic balloon pump (IABP) or percutaneous left ventricular assist device (pLVAD) insertion i.e. \=moderate aortic regurgitation (AR), severe peripheral vascular disease (PVD) prohibiting insertion of either device
  • •6\. Mechanical aortic valve replacement (AVR)

Outcomes

Primary Outcomes

Not specified

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