Changes in left ventricular afterload after aortic valve replacement in severe aortic stenosis patients
Not Applicable
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0003639
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 29
Inclusion Criteria
severe aortic stenosis patients (aortic valve area < 1.0 cm2) who undergo elective aortic valve replacement
-left ventricular ejection fraction =50% on preoperative transthoracic echocardiography
-mean transaortic pressure gradient = 40 mmHg on preoperative transthoracic echocardiography
Exclusion Criteria
-patietns who show preoeprative atrial fibrillation or atrial flutter
-patients with inotropic drug or mechanical assist device to stabilize the hemodynamics
-patients with moderate or severe aortic regurgitation combined with aortic stenosis
-patients with moderate or severe disease in other valve
-patietns who undergo emergency surgery
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method arterial elastance
- Secondary Outcome Measures
Name Time Method systemic vascular resistance;arterial compliance;valvuloarterial impedance