Insulin Sensitivity of the Brain in Pathogenesis of Diabetes Mellitus Type 2

Not Applicable

• Conditions: Human Physiology of Energy Homeostasis
• Interventions: Drug: Human insulin; Drug: Saline

• Registration Number: NCT00638209
• Lead Sponsor: University Hospital Tuebingen

Brief Summary

The purpose of the study is to investigate whether insulin sensitivity of the human brain correlates with insulin sensitivity of the liver.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-02
• Status Verified: 2008-03
• Study First Submitted: 2008-03-12
• Study First Submitted QC: 2008-03-18
• Last Update Submitted: 2008-03-18
• Study First Posted: 2008-03-19
• Last Update Posted: 2008-03-19
• Primary Completion: 2010-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• Age 18-70 Risk factor(s) for type 2 diabetes (e.g. overweight, family history of diabetes)

Exclusion Criteria

• Type 2 diabetes pregnancy acute or chronic diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
I	Human insulin	-
P	Saline	-

Primary Outcome Measures

Name	Time	Method
Insulin effect on cortical function (spectral analysis)	2 weeks

Trial Locations

Locations (2)

University Hospital Tuebingen, Internal Medicine IV; 🇩🇪 Tuebingen, Germany

University Hospital Tuebingen; 🇩🇪 Tuebingen, Germany