Acute effects of exercise in heart failure - a pilot study

Completed

• Conditions: decompensatio cordis; heart decompensation; heart failure; 10019280

• Registration Number: NL-OMON37247
• Lead Sponsor: Fysiologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 45

Inclusion Criteria

Patient group
- Patients diagnosed with heart failure NYHA class II/III
- >= 18 years of age
- Mentally able/allowed to give informed consent;Control group
- Subjects free of cardiovascular disease and/or cardiovascular medication
- >= 18 years of age
- Mentally able/allowed to give informed consent

Exclusion Criteria

- Contra-indications for exercise testing
- Serious co-morbidity;For the telemetric temperaturepill, additional exclusioncriteria have been formulated.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Brachial artery blood flow patterns during leg exercise; retrograde and<br /><br>antegrade shear rate, expressed in oscillatory index.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Thermoregulatory changes (skin and core body temperature)<br /><br>Autonomic function (heart rate variability)<br /><br>Cardiac troponin-release and N-terminal B-type natriuretic peptide concentration<br /><br>Heart rate and blood pressure</p><br>