Estimating lower airway aerosol inhalant deposition by using Functional Respiratory Imaging (FRI), a novel imaging technology, in asthma patients
Not Applicable
- Conditions
- Bronchial asthma
- Registration Number
- JPRN-UMIN000022840
- Lead Sponsor
- Department of Respiratory Medicine and Allergology, Kindai University, Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 6
Inclusion Criteria
Not provided
Exclusion Criteria
1) Obviously has a chronic obstructive pulmonary disease (COPD). 2) Has a respiratory tract infection. 3) Determined by the investigator to be ineligible.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Deposition rate of peripheral airways calculated by FRI-based operation.
- Secondary Outcome Measures
Name Time Method 1) The following indexes are calculated by FRI-based operation a. Deposition rate of airways and lobes b. Airway volume and airway resistance 2) Endpoints for respiratory function testing (after inhaling a bronchodilator) FEV1, %FEV1, FEV1%, FVC, Vdot50, Vdot25, %Vdot50, and %Vdot25 3) Endpoints for IOS measurement (after inhaling bronchodilator) R5, R20, R5-R20, X5, AX, Fres, R5 ex-in, R20 ex-in, R5-R20 ex-in, X5 ex-in, AX ex-in and Fres ex-in 4) Correlation between peripheral airway resistance and deposition rate