Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage

Completed

• Conditions: Subarachnoid Hemorrhage; Cerebral Vasospasm; Hydrocephalus

• Registration Number: NCT01799018
• Lead Sponsor: State University of New York - Upstate Medical University

Brief Summary

The purpose of this study is to determine the role of Proteomics and Metallomics in Cerebral Vasospasm following Subarachnoid Hemorrhage

Detailed Description

Not available

Study Timeline

• Study Start: 2011-04
• Study First Submitted: 2012-12-12
• Study First Submitted QC: 2013-02-22
• Study First Posted: 2013-02-26
• Primary Completion: 2013-06
• Study Completion: 2013-06
• Status Verified: 2014-11
• Last Update Submitted: 2014-11-19
• Last Update Posted: 2014-11-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Non traumatic SAH documented by CT scan
• Patient with SAH who would need external ventricular drain (EVD) for the management of hydrocephalus
• Patients with normal pressure Hydrocephalus that require an external drain
• Control (non - hemorrhagic) group - CSF collected from patients with posterior fossa tumor or stroke with EVD in place for the management of hydrocephalus.

Exclusion Criteria

• Recent infection within last 1 month of presentation- can increase inflammatory markers
• Recent surgery or acute myocardial infarction within last 1 month of presentation
• Age > 89 years or < 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Protein identification and concentration	For the duration of CSF drainage, or until the 21st day after admission.
Metal ion identification and concentration	For the duration of CSF drainage, or until the 21st day after admission.

Trial Locations

Locations (1)

State University of New York Upstate Medical University; 🇺🇸 Syracuse, New York, United States