Imaging Inflammation of the Cervical Dorsal Root Ganglion before and after Anterior Cervical Discectomy: a Pilot study

Recruiting

• Conditions: Cervical radiculair pain; 10028377; 10041543

• Registration Number: NL-OMON41414
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Radicular pain of the lowar cervical spine (C4-7) with an indication for anterior cervical discectomy

Exclusion Criteria

Age below 18 and above 65 years; Pregnancy; Lack of cooperation of the patient; Patients who are not able to complete the questionnaires, according to the referring doctor; allergy to contrast dye; diabetics.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter of the additional study is detection of the site of<br /><br>inflammation of the dorsal root ganglion with FDG-PET/CT. Also, if increased<br /><br>tracer activity is detected at the site of the affected ganglion, standard<br /><br>uptake values (SUVs) will be determined. It will be investigated whether the<br /><br>values of the SUVs correlate with the severity of the patients* complaints and<br /><br>whether at repeat investigation (after the anterior cervical discectomy) there<br /><br>is a change in this outcome measurement.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The influence of treatment on the intensity of pain, the global perceived<br /><br>effect.</p><br>