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Role of Brahmi in treatment of Alzheimers disease

Phase 2
Conditions
Health Condition 1: null- Alzheimerâ??s disease, Mild Cognitive Impairment-AD
Registration Number
CTRI/2018/04/013388
Lead Sponsor
Postgraduate Institute of Medical Education and Research
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Age > 50 yrs

2. DSM IV Criteria for Dementia

3. Diagnostic criteria for MCI, AD (Duboisâ??s criteria), VaD (DSM IV TR)

4. Study informant available

5. Adequate vision and hearing for neuropsychological testing

6. Normal appropriate laboratory tests

7. All subjects and study informants signed written consent

Exclusion Criteria

1. Young onset dementia

2. Diagnosis of vascular dementia, Fronto-temporal dementia

3. Secondary acquired causes of dementia

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in dementia rating scales (Alzheimerâ??s Disease Assessment Scale (Cognitive) and PGI (Postgraduate Institute) Memory scale at 3,6,9 and 12 monthsTimepoint: 4 years
Secondary Outcome Measures
NameTimeMethod
Verbal fluency â?? Controlled oral word test (phonemic) & Animal Names test (categorical), Quality of life â?? AD, ADCS (Alzheimerâ??s Disease Cooperative Study) Activities of Daily Living Inventory, Compliance to treatment and number of adverse eventsTimepoint: 4 years
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