Control and Treatment of Outpatient Children with Asthma

Not yet recruiting

• Conditions: Asthma

• Registration Number: NCT06837584
• Lead Sponsor: Beijing Children's Hospital

Brief Summary

The aim of this study is to comprehensively understand the disease control and management status of children with asthma in China, as well as the types of airway inflammation. The findings of this survey will help improve the asthma control level in Chinese children, facilitate future patient education, and guide rational medication use. Moreover, it will provide important evidence for health decision-making departments to better allocate and utilize medical resources.

Detailed Description

Bronchial asthma (hereinafter referred to as asthma) is the most common chronic respiratory disease in children. It severely affects the physical and mental health of children and imposes a huge economic burden on families and society, consuming a large amount of medical and health resources. In recent years, the prevalence of asthma in children worldwide has generally continued to rise. Data from the Global Burden of Disease database in 2019 showed that the prevalence of asthma in children aged 0-9 years was 4.21%, in children aged 10-14 years was 4.10%, and in adolescents aged 15-19 years was 3.00%. In China, over the past 20 years, the prevalence of asthma in children has also shown an overall upward trend, increasing from 0.91% in 1990 to 1.54% in 2000, and then to 3.02% in 2010. Thanks to the continuous efforts of several generations of pediatricians, the level of standardized diagnosis and treatment of childhood asthma has significantly improved. However, the control of asthma in children still faces many challenges.

The purpose of this study is to comprehensively understand the disease control and management status of children with asthma in China, as well as the types of airway inflammation. The findings of this survey will help improve the asthma control level in Chinese children, facilitate future patient education, guide rational medication use, and provide important evidence for health decision-making departments to better allocate and utilize medical resources.

Study Timeline

• Status Verified: 2025-02
• Study First Submitted: 2025-02-15
• Study First Submitted QC: 2025-02-15
• Last Update Submitted: 2025-02-15
• Study First Posted: 2025-02-20
• Last Update Posted: 2025-02-20
• Study Start: 2025-03-01
• Primary Completion: 2026-03-01
• Study Completion: 2026-03-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 42000

Inclusion Criteria

• Age between 2 and 16 years old；Children who have been diagnosed with asthma for more than 3 months;Children who have had asthma symptoms or asthma treatment within the past 12 months.

Exclusion Criteria

• Children diagnosed with other respiratory diseases such as bronchiectasis, bronchiolitis, cystic fibrosis, and pneumonia; Children who have participated in any interventional clinical studies related to asthma within the 3 months prior to enrollment in this study; Children whose parents, legal representatives, or guardians do not agree to participate in this study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Asthma control level	3 months before and at the time of enrollment	Asthma control was assessed with ACT scale
The proportion of type 2 inflammation	3 months before and at the time of enrollment	Blood EOS and IgE were used to judge