Effect of Septal Nasal Deviation on carotid intima media thickness

Not Applicable

• Conditions: nasal obstruction; Nasal septal deviation; Respiratory - Other respiratory disorders / diseases; Cardiovascular - Diseases of the vasculature and circulation including the lymphatic system

• Registration Number: ACTRN12619000347167
• Lead Sponsor: Selcuk University, Faculty of medicine hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-05
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Individuals who admitted to our outpatient clinic with the complaint of nasal obstruction and were required septoplasty
as a control group, volunteer individuals without septum deviation or upper airway obstruction
Patients who have BMI under 35
Patients without diagnosed a cardiovascular and pulmonary disease
Patients age: 18-65 years

Exclusion Criteria

1. patients used smoking and alcohol
2. DM, Hypertension
3. hypercholesterolemia
4. Coronary artery disease
5. History of myocardial infarction,
6. Active infection
7. Asthma, allergic rhinitis
8. A history of cerebrovascular disease
9. Immune-related diseases (eg ankylosing spondylitis, SLE, Behçet)
10. Under 18 years and over 65 years
11. Chronic sinusitis,
12. Cardiac diseases
13. Chronic obstructive pulmonary disease
14. Using ACE inhibitor, Diuretic, angiotensin II receptor blocker and beta blocker
15.Individuals with BMI> 35
16. Patients with a history of known hyperthyroidism
17.Pregnant women, breastfeeding women and patients with poor general condition

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of nasal obstruction will be evaluated VAS scale.[Evaluation of Visual Analog Scale (VAS) in both groups will be performed by the otorhinolaryngologist before the initiation of the study.];Assessment of Nasal Obstruction Symptom Evaluation (NOSE) scale in participants[Assessment of Nasal Obstruction Symptom Evaluation (NOSE) scale in both groups will be performed by the otorhinolaryngologist before the initiation of the study.]

Secondary Outcome Measures

Name	Time	Method
Electrocardiography measurement will be performed in both groups. The electrocardiography will be performed to define whether cardiac pathology such as arrhythmia, myocardial infarction.[Evaluation of the electrocardiography will be performed by the cardiologist in both groups.];The carotid intima-media thickness measurement with B-mode ultrasonography will be performed in both groups.[Assessment of carotid intima-media thickness with B-mode ultrasonography will be performed by the cardiologist in both groups.];The measurement of blood cholesterol level will be performed in both groups.[The measurement will be performed during the preoperative tests in patients.]