The additive effect of Imaginary Rescripting for treating depressive symptoms in childhood trauma related depression in adolescence: A multiple baseline study among 15 adolescents

Recruiting

• Conditions: Major Depressive Disorder; Depression; Childhood Trauma; 10027946

• Registration Number: NL-OMON53322
• Lead Sponsor: GGZ Oost Brabant (Rosmalen)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all
of the following criteria:
• Adolescents aged between 16 and 23 years in care at GGZ Oost Brabant
• Mastery of Dutch language
• Moderate to severe depression after 3 months of Care As Usual (CAU) for
depression:
o Score > 26 on the IDS-SR (Bernstein et al., 2007)
o DSM-5 diagnosis of depression, confirmed with the MDD part of the Mini
International Neuropsychiatric Interview - Simplified (MINI-S), Dutch version
1.1. for DSM-5 (Overbeek & Schruers, 2019).
• Moderate to severe childhood trauma (CT) before the age of 16
o At least one score above validated cut-offs for the CT subtypes of the
Childhood Trauma Questionnaire - Short Form (CTQ-SF; Bernstein & Fink, 1998;
physical neglect: score >10; emotional neglect: score >15; sexual abuse: score
>8; physical abuse: score >10; emotional abuse: score >13)
• In the case of suicidal ideation: The patient is in possession of an up to
date safety plan
• Patient is inclined to give written informed consent

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
• There is still immediate physical threat/harm/violence in the adolescent*s
life which acquires attention
i• There is a history of trauma-focused therapy with EMDR, imagery exposure or
Imagery Rescripting in regard to the traumatic childhood event
• There is alcohol/drug dependence or other sever psychiatric comorbidity (e.g.
bipolar disorder, psychotic disorder) that requires clinical attention
• There is a primary DSM-5 diagnosis of PTSD or Acute Stress disorder (ASD)
• There is acute suicide risk with an indication for hospitalization (further
elaborated in the research protocol p.18)

Study & Design

• Study Type: Interventional
• Study Design: Not specified