NL-OMON44090
Completed
Not Applicable
Cerebrovascular manifestations of vascular Amyloid deposition in HCHWA-D | An assessment of the cerebrovascular reactivity in Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D) patients using Magnetic Resonance Imaging and transcranial Doppler. - Cerebrovascular reactivity in HCHWA-D
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hereditary Cerebrale Amyloïd Angiopathie (hCAA)
- Sponsor
- eids Universitair Medisch Centrum
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Symptomatic HCHWA\-D patients:
- •\* HCHWA\-D with a genetic\-based diagnosis
- •\* One or more radiological confirmed hemorrhages
- •\* Ability and willingness to provide written informed consent
- •\* Age: older than 18 years;Control subjects:
- •\* Age and gender matched with the HCHWA\-D subjects, older than 18 years
- •\* Ability and willingness to provide written informed consent
Exclusion Criteria
- •\* Presence of other known cerebrovascular diseases not related to CAA: diabetes, hypertension, overt atherosclerotic disease
- •\* Contra indications to MR imaging
- •\* Contra indications to CO2 stimulation
- •\* Severe physical restriction / inability to be scanned, such as weight above 120 kg.
Outcomes
Primary Outcomes
Not specified
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