Measurement of Colloid Osmotic Pressure in Plasma and Interstitial Fluid in Children

Completed

• Conditions: Colloid Osmotic Pressure

• Registration Number: NCT01044641
• Lead Sponsor: Haukeland University Hospital

Brief Summary

The purpose of this study is to identify normal values of colloid osmotic pressure in interstitial fluid and plasma in healthy children between 2 and 10 years.

Detailed Description

Measurements of colloid osmotic pressure (COP) by sampling of interstitial fluid from subcutaneous tissue and plasma are well documented in animal models and human adult studies. COP plays a major role in transcapillary fluid balance and is valuable in fluid therapy planning in critically ill patients. There are no data regarding interstitial fluid COP values in neither sick nor healthy children. Sampling of interstitial fluid by the wick method in children who is under general anaesthesia (ear-nose-throat operations) gives the opportunity to identify normal COP values in this age group.

Study Timeline

• Study Start: 2009-12
• Study First Submitted: 2010-01-06
• Study First Submitted QC: 2010-01-07
• Study First Posted: 2010-01-08
• Primary Completion: 2013-05
• Study Completion: 2013-05
• Status Verified: 2014-07
• Last Update Submitted: 2014-07-03
• Last Update Posted: 2014-07-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 99

Inclusion Criteria

• Children from 2 to 10 years

Exclusion Criteria

• Medication
• Ongoing illness
• Syndromes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Colloid osmotic pressure	60 minuttes after wick insertion

Trial Locations

Locations (1)

Haukeland University Hospital; 🇳🇴 Bergen, Norway