Colloid Oncotic Pressure as indicator of hemodilution in cardiac surgery with cardiopulmonary bypass
- Conditions
- Coronary disease, cardiac valve disease
- Registration Number
- NL-OMON22437
- Lead Sponsor
- Amsterdam UMC, VUmc location
- Brief Summary
ot yet, study is ongoing
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
•Informed consent
•Patients undergoing elective cardiac surgery
Exclusion Criteria
•Emergency operations
•Patients with previous heart surgery
•Patients undergoing elective thoracic aortic surgery.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method •To determine the changes in COP between different priming fluids during cardiac surgery with CPB
- Secondary Outcome Measures
Name Time Method •Is the serum albumin level correlated with the level of COP during cardiac surgery with CPB?<br>•Is the change of COP during cardiac surgery with CPB associated with a change in extravascular fluid shift (positive fluid balance, weight gain, mean arterial pressure)?<br>•Is the change of COP during cardiac surgery with CPB associated with intravascular hemodilution (hemoglobin, hematocrit, blood product use)?<br>•Is the change of COP during cardiac surgery with CPB associated with blood loss and hemostasis (platelet count, fibrinogen, use of coagulation factors concentrate)?<br>