MedPath

Enhanced postoperative mobilization and biotracking after colorectal oncological resection (INTENSE-Study)

Not Applicable
Recruiting
Conditions
Elective minimally invasive colorectal surgery for CRC
Registration Number
DRKS00033443
Lead Sponsor
Klinik für Allgemein-, Viszeral- und Thoraxchirurgie, Universitätsklinikum Hamburg-Eppendorf
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
100
Inclusion Criteria

All patients scheduled for elective minimally invasive (laparoscopic or robot-assisted) colorectal surgery for CRC
- no intended multivisceral resection (exceptions are small atypical liver wedge resections, biopsies, abdominal wall resection, partial prostate/bladder resection, adnexectomy, cholecystectomy)
- preoperatively mobile patients (e.g., not wheelchair bound)
- no contraindication for wearing activity tracker devices

Exclusion Criteria

- primary open surgical technique

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Composed of two hierarchical endpoints:<br>1. postoperative duration to 5 predefined DCs<br>- GI-2 (a validated composite measure of GI recovery defined as the interval from surgery until first passage of stool and tolerance of solid intake for 24h in the absence of vomiting)<br>- ambulation independently or at the preoperative level<br>- no intravenous fluids or pain medication<br>- no fever and a serum C-reactive protein concentration <80 mg/l) <br><br>2. Number of steps during postoperative Days 1-5, as recorded using activity tracking wristbands.
Secondary Outcome Measures
NameTimeMethod
- length of hospital stay<br>- 30-day mortality, and 30-day overall morbidity according to the Clavien-Dindo classification <br>- number of steps on POD 1-5<br>- highest mobility level measured by the CHARMI®-Index (Liebl et al. PLOS ONE 2016)<br>- biodiversity data from the activity tracker (calorie consumption, sleep phases, oxygen saturation, heart rate on POD 1-5 and correlation with complications such as an increase in infection levels [white blood count, C-reactive protein]) will be analysed.<br>- Lebensqualitätserhebung (EQ-5D-3L)<br>
© Copyright 2025. All Rights Reserved by MedPath