Effects of Glycerol Hyperhydration on Running Economy in Long-Distance Runners
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Maximal oxygen consumption (VO₂peak) (ml/kg/min)
研究概览
简要总结
The aim of this study was to evaluate the effects of hyperhydration with glycerol on running economy (RE) in trained runners. The main questions sought to be answered are:
- Does hyperhydration with glycerol improve running economy?
- Are there beneficial effects on physical performance?
The researchers will conduct a clinical trial with 30 runners (15 men, 15 women) in three sessions. In the first session, VO2peak was determined and running speeds were established for sessions 2 and 3. In the second session, participants performed a stress test. In the second session, participants performed a running test in the euhydrated state under fluid restriction, and in the third session, with glycerol supplementation (22 ml/kg sports drink + 1.2 g/kg glycerol). Variables such as caloric cost unit (CCU), oxygen cost unit (OCU), heart rate (HR), body temperature (BT) and perceived exertion (RPE) were evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Competitive runners with a minimum record of 4.2 min/km.
- •Age between 18 and 35 years old
- •Apparently healthy athletes
- •Signature of informed consent form
排除标准
- •Presence of comorbidities that could alter the study variables (such as arterial hypertension, hyperthyroidism or heart disease).
- •Consumption of medications or stimulants (such as caffeine or diuretics) 48 hours before the tests.
结局指标
主要结局
Maximal oxygen consumption (VO₂peak) (ml/kg/min)
时间窗: In the first evaluation session to be held in the first week of a total of 3 weeks of study duration
Session 1: VO2peak measurements through an incremental treadmill test with 2 km/h speed increments every 3 minutes, maintaining a constant 1% incline. The test started at 6 km/h for all participants and continued until volitional exhaustion
Running economy (CE)
时间窗: In the first evaluation session to be held in the first week of a total of 3 weeks of study duration
Test under Hydration Restriction (No-GLY): As a mandatory requirement, participants reported to the laboratory in a euhydrated state (USG: 1.018-1.024) prior to the start of the test, following the criteria outlined in previous research \[31\]. They ran for 15 minutes on a treadmill at a speed equivalent to 65%-70% of their VO2peak from the first session. During the test, running economy variables such as the caloric cost unit (CCU), oxygen cost unit (OCU), body temperature (BT), rating of perceived exertion (RPE) via the Borg scale, and hydration status were measured. Running Economy Calculation: i) The caloric cost unit (CCU) was calculated via the following equation \[25\]: CCU =((VO2 x δ x 1000)/(V x MC)) x 100 where VO2 is the oxygen consumption rate (L/min); δ is the kcal/L of oxygen based on the respiratory exchange ratio (RER); V is the speed (m/min); and MC is the body mass (kg).
次要结局
- Body temperature(Body temperature was measured during sessions 2 (No Gly) and 3 (Gly) at the following times: at minute 0 (prior to the start of each test) and at minutes 5, 10 and 15 during a treadmill test.)
- Perception of exertion(It was applied during the evaluation of the stress tests to determine the Vo2peak and Running Economy.)
- Sweating rate.(In sessions 1 and 2, urine specific gravity (USG) was assessed, which was one of the key criteria for determining whether subjects could continue in the study without being eliminated.)
研究者
Cesar Octavio Ramos Garcia, PhD
Chief Research Officer (CRO)
Iberoamerican Institute of Sports Science and Human Movement