Stimuleren van het onwillekeurige zenuwstelsel met perioperatieve voeding bij patiënten die een darmoperatie ondergaan.
Completed
- Conditions
- Postoperative ileus, anastomotic leakage, colorectal surgery, enteral nutrition, intestinal damage, inflammation
- Registration Number
- NL-OMON20551
- Lead Sponsor
- Catharina Hospital Eindhoven
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 280
Inclusion Criteria
1.Elective segmental colorectal resection with primary anastomosis
2.Written informed consent
Exclusion Criteria
1.Previous gastric or oesophageal resection
2.Pre-existent or creation of ileostoma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Postoperative ileus<br />
- Secondary Outcome Measures
Name Time Method 1.Aspiration pneumonia<br /><br>2.Preoperative gastric volumes<br /><br>3.Length of functional recovery<br /><br>4.Length of stay<br /><br>5.The local and systemic inflammatory response <br /><br>6.Intestinal barrier integrity<br /><br>7.Surgical complications according to Clavien-Dindo<br /><br>8.Need for additional surgical, radiological or endoscopic interventions<br /><br>9.Need for ICU admission and total length of ICU stay<br /><br>10.Health related quality of life<br>11. Anastomotic leakage<br>12. Cost effectiveness ratios