Effects of Transcranial Oscillatory Direct Current Stimulation on the Functions of Cerebral Cortex in Healthy Subjects

Not Applicable

Recruiting

• Conditions: Healthy Subjects; Transcranial Direct Current Stimulation; Motor Evoked Potential
• Interventions: Device: toDCS 2mA 1Hz; Device: toDCS 2mA 10Hz; Device: tDCS 1mA; Device: sham

• Registration Number: NCT06076044
• Lead Sponsor: The First Hospital of Hebei Medical University

Brief Summary

To investigate the effect of transcranial oscillatory direct current stimulation on functions of cerebral cortex (cortical excitability and frequency of eeg) in healthy subjects

Detailed Description

Not available

Study Timeline

• Study Start: 2023-06-01
• Study First Submitted: 2023-09-21
• Study First Submitted QC: 2023-10-07
• Study First Posted: 2023-10-10
• Primary Completion: 2023-11-30
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-22
• Last Update Posted: 2024-02-23
• Study Completion: 2024-03-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Male
• Target Recruitment: 15

Inclusion Criteria

• Healthy male
• Age ranges from 20 to 30 years old
• No history of neurological or psychiatric diseases, no history of chronic illness
• No positive results were found in the examination of the nervous system
• All right-handed according to Edinburgh Handedness Inventory
• The subjects voluntarily participated in this study and signed an informed consent form

Exclusion Criteria

• Individuals with severe illnesses
• Previous history of brain surgery or epilepsy
• Individuals who experience changes in physical condition during the experiment
• Individuals with metal implants, such as pacemakers, DBS therapists, stents, etc
• Alcoholics

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
healthy subjects	tDCS 1mA	healthy male subjects aged 20-30 years
healthy subjects	sham	healthy male subjects aged 20-30 years
healthy subjects	toDCS 2mA 1Hz	healthy male subjects aged 20-30 years
healthy subjects	toDCS 2mA 10Hz	healthy male subjects aged 20-30 years

Primary Outcome Measures

Name	Time	Method
Power Spectral Density of EEG	before treatment and right after treatment	The rest state EEG of the subjects was collected
MEP	before treatment and 20, 30, 40, 50, 60 minutes after treatment	Motor evoked potentials of the right abductor pollicis brevis were collected

Trial Locations

Locations (1)

the First Hospital of Hebei Medical University; 🇨🇳 Shijiazhuang, Hebei, China