Evaluation of efficacy of Ziziphus Vulgaris formula to prevent drug induced liver enzyme disorder” in pulmonary tuberculosis Patients

Phase 3

Recruiting

Conditions: drug-induced hepatotoxicity.
Toxic liver disease, unspecified
K71.9

Registration Number: IRCT20181107041586N1

Lead Sponsor: Sari University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

Declaration of written consent of the volunteer for participation in the trial
Age from 30 to 65 years
A new diagnosis of pulmonary tuberculosis by an infectious disease specialist or a health center doctor
No relapse or drug resistance
No history of HIV-positive
No history of renal failure
No history of all types of acute and chronic and alcoholic hepatitis
No history of cirrhosis
No Pregnancy and lactation

Exclusion Criteria

Patients under treatment with other herbal supplements
Lack of appropriate verbal communication
Patients with Oral intolerance
No tendency to take herbal medicine
No tendency to consume syrup

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum level of alanine aminotransferase. Timepoint: At the beginning of the study (before the intervention),The end of the second week and at the end of the intervention. Method of measurement: Biochemical tests.;Serum level of aspartate aminotransferase. Timepoint: At the beginning of the study (before the intervention),The end of the second week and at the end of the intervention. Method of measurement: Biochemical tests.;Serum level of Alkalin phosphatase. Timepoint: At the beginning of the study (before the intervention),The end of the second week and at the end of the intervention. Method of measurement: Biochemical tests.

Secondary Outcome Measures