Fast-track Giant Ventral Hernia Repair
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Time to discharge
研究概览
简要总结
The implementation of an enhanced recovery pathway after giant ventral hernia repair, including preoperative high-dose steroid is examined prospectively and compared with a group of historic controls.
详细描述
All patients operated on for a large incisional hernia are treated according to the study protocol. Patients are given high-dose glucocorticoid preoperative and the aim is to discharge patients at postoperative day 3.
Morbidity, length of stay, pain, nausea and pulmonary function are among registered outcomes compared with a historic control group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Horizontal fascia defect > 10 cm on computed tomography scan
- •Planned elective open incisional hernia repair
排除标准
- •Known allergy against glucocorticoid treatment
- •Insulin-treated diabetes
- •Gastric ulcer diagnosed within four weeks preoperative
- •Steroid-treated immune disease
- •Planned intestinal anastomosis concomitant to hernia repair
结局指标
主要结局
Time to discharge
时间窗: Participants will be followed for the duration of hospital stay, an expected average of 72 hours
Time from surgery to discharge \[Hours\].
次要结局
- Fatigue(Preoperative and for the duration of hospital stay, an expected average of 3 days)
- Pain from supine to standing(Preoperative and for the duration of hospital stay, an expected average of 3 days)
- C-reactive protein from venous blood sample(Preoperative and for the duration of hospital stay, an expected average of 3 days)
- Pain when walking 6 meters(Preoperative and for the duration of hospital stay, an expected average of 3 days)
- Vomiting episodes(Participants will be followed for the duration of hospital stay, an expected average of 3 days)
- Continuous transcutaneous saturation(From surgery to postoperative day 3 at 12 pm)
- Nausea(Preoperative and for the duration of hospital stay, an expected average of 3 days)
- Time to bowel function(For the duration of postoperative hospital stay, an expected average of 72 hours)
- Ear temperature(Preoperative and for the duration of hospital stay, an expected average of 3 days)
- Detailed reason for not being discharged if criteria are otherwise fulfilled(From surgery and for the duration of hospital stay, an expected average of 3 days)
- Daily wound drain production(From surgery and for the duration of hospital stay, an expected average of 3 days)
研究者
Kristian Kiim Jensen
MD, PHD student
Bispebjerg Hospital