Therapeutic Efficacy of Intense Pulsed Light in the Treatment of Chalazion

Not Applicable

• Conditions: Chalazion
• Interventions: Device: IPL; Procedure: Conservative treatment or excision with curettage

• Registration Number: NCT05512572
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

Study method: This test screened the subjects first, and proposed to include 50 subjects with primary or recurrent eyelid plate gland cysts without obvious surgical indications. All subjects underwent three strong pulsed light therapy combined with eyelid plate gland massage, treatment of local anesthesia eye drops, and metal pads were placed in conjunctival sac protection. Eye protection, using the M22 strong pulsed light small optical treatment head of the medical company, energy selection 14-16J/cm2, laser position is selected on the upper and lower eyelids, 3mm away from the root of the eyelashes. Each interval is 3 weeks. Eye-related examinations were performed before treatment and 3 times after treatment. The evaluation content included: ocular surface, slit lamp observation, anterior segment photography, intraocular pressure, vision, corneal fluorescein staining, tear film rupture time, eyelid plate gland evaluation, eyelid plate gland cyst relief, eyelid plate gland cyst recurrence rate.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-23
• Status Verified: 2021-09
• Primary Completion: 2021-10-30
• Study First Submitted: 2022-08-21
• Study First Submitted QC: 2022-08-21
• Study First Posted: 2022-08-23
• Last Update Submitted: 2022-09-17
• Last Update Posted: 2022-09-21
• Study Completion: 2023-08-23

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients had primary or recurrent eyelid plate gland cyst without obvious surgical indications

Exclusion Criteria

• (1) any intraocular inflammation, ocular infection, allergy, ocular surgery, or ocular trauma in the past 6 months; (2) any eyelid diseases or structural abnormality; (3) any systematic diseases may lead to dry eye or MGD; (4) skin cancer or pigmented lesion in the treatment zone.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental group	IPL	Receiving IPL-MGD treatment.
Control group	Conservative treatment or excision with curettage	Another set of age, sex and diagnosis matched consecutive cases of chalazion, who received conservative treatment or excision with curettage but without IPL-MGX treatment as a control (Non-IPL group).

Primary Outcome Measures

Name	Time	Method
Recurrence rate of chalazia	An average of 1 year	The recurrence of the chalazia

Trial Locations

Locations (1)

Second Affiliated Hospital of Zhejiang University Hospital; 🇨🇳 Hangzhou, Zhejiang, China