ISRCTN73579730已完成不适用
Do xanthine oxidase inhibitors reduce left ventricular hypertrophy and endothelial dysfunction in normotensive patients with chronic stable angina?: a randomised double-blind placebo-controlled single-centre trial
niversity of Dundee (UK)0 个研究点目标入组 66 人开始时间: 2009年5月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Both males and females, adults (No specific age limits)
- •2. Patients with blood pressure <150/90 mmHg
- •3. Patients with left ventricular hypertrophy
- •4. Patients with stable angina
排除标准
- •1. Patients with gout or already on allopurinol
- •2. Patients who have had a previous adverse reaction to allopurinol
- •3. Patients already on azathioprine
- •4. Patients with renal dysfunction (estimated glomerular filtration rate (eGFR) <60 ml/min)
- •5. Patients with heart failure or a left ventricular ejection fraction (LVEF) <45%
- •6. Patients who have conditions that would exclude them from undergoing an Magnetic Resonance Imaging (MRI) test such as pacemakers or any metal implants in their body
- •7. Patients who suffer from claustraphobia
- •8. Patients with cancer or lifethreatening illnesses
- •9. Patients who are unable to provide informed consent (e.g., learning disabilities)
- •10. Pregnancy or breastfeeding patients
研究者
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