Ventilator-associated Pneumonia (VAP) and Humidification System

Phase 4

• Conditions: Ventilator-associated Pneumonia
• Interventions: Device: HME filter Twin Star 55, Drager Medical, Germany; Device: Heated humidification

• Registration Number: NCT01546974
• Lead Sponsor: Hospital Sao Domingos

Brief Summary

The purpose of this study is to determine which humidification system is more effective in preventing pneumonia in mechanically ventilated patients. The study will compare a heat and moisture exchanger versus heated humidification.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-11
• Status Verified: 2012-01
• Study First Submitted: 2012-03-03
• Study First Submitted QC: 2012-03-06
• Last Update Submitted: 2012-03-06
• Study First Posted: 2012-03-07
• Last Update Posted: 2012-03-07
• Primary Completion: 2013-11
• Study Completion: 2014-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 306

Inclusion Criteria

• Patients expected to require mechanical ventilation for at least 48 hours

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Exclusion Criteria

• Patients < 18 yo and pregnant

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
HME filter	HME filter Twin Star 55, Drager Medical, Germany	-
Heated humidificator MR 730 Fisher & Paykel	Heated humidification	-

Primary Outcome Measures

Name	Time	Method
VAP incidence

Secondary Outcome Measures

Name	Time	Method
Duration of mechanical ventilation

Trial Locations

Locations (1)

Hospital Sao Domingos; 🇧🇷 Sao Luis, MA, Brazil