Effects of vitamin D and/or aquatic exercise on IL-1ß and IL-1RA serum levels and behavior of children with autism spectrum disorder

Not Applicable

• Conditions: Autism Spectrum Disorder.; Autistic disorder; F84.0

• Registration Number: IRCT20180503039517N5
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 October 2020

Recruitment & Eligibility

• Status: Complete
• Sex: Male
• Target Recruitment: 80

Inclusion Criteria

psychiatrist –diagnosed ASD (by Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition (DSM-V))
Male gender
aged 6-8 years
no change in any medical, dietary or behavior treatment during the study
parental informed consent

Exclusion Criteria

Having comorbid disability or other Neuro-cognitive disorders
receiving vitamin D supplements in the last 6 months

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IL-1B serum levels. Timepoint: One week before starting and one week after terminating of intervention. Method of measurement: Diaclone human kit for IL-1B.;IL-1ra serum levels. Timepoint: One week before starting and one week after terminating of intervention. Method of measurement: ZellBio human kit for IL-1RA.;Vitamin D serum level. Timepoint: One week before starting and one week after terminating of intervention. Method of measurement: Pars Azmoon human kit.;Stereotypic behavior. Timepoint: One week before starting and one week after terminating of intervention. Method of measurement: Gars-2, stereotypic behaviors subscale.