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Clinical Trials/NCT01628276
NCT01628276
Completed
Not Applicable

Brain Functional Connectivity Changes Following Cognitive Rehabilitation in Multiple Sclerosis: an fMRI Study

Sina Hospital, Iran1 site in 1 country45 target enrollmentJuly 2012
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ConditionsMS (Multiple Sclerosis)

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
MS (Multiple Sclerosis)
Sponsor
Sina Hospital, Iran
Enrollment
45
Locations
1
Primary Endpoint
functional connectivity
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This trial seeks to investigate brain network changes following cognitive rehabilitation in MS patients. The investigators hypothesize that rehabilitation interventions improve connectivity in the brain.Novel Magnetic Resonance Imaging technique is performed to investigate changes in brain plasticity.

Registry
clinicaltrials.gov
Start Date
July 2012
End Date
October 2013
Last Updated
11 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Sina Hospital, Iran
Responsible Party
Principal Investigator
Principal Investigator

Mohammad Ali Sahraian

Vice President

Sina Hospital, Iran

Eligibility Criteria

Inclusion Criteria

  • •Definitive MS diagnosis
  • •Right handedness
  • •No relapse in past 6 weeks
  • •Willing to consent and participate in the study

Exclusion Criteria

  • •Pregnancy
  • •Left handedness
  • •Neurologic or psychiatric disorder other than MS

Outcomes

Primary Outcomes

functional connectivity

Time Frame: 0, 2nd, 4th Month

Changes in correlation of brain activity in different regions of brain as assessed by Blood Oxygenation Level Dependent (BOLD) signal

Study Sites (1)

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