Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Nel Confronto Con la Tecnica Tradizionale Single-shot Nei Pazienti Sottoposti ad Artroprotesi d'Anca. Trial Randomizzato Controllato
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- SBP change
研究概览
简要总结
Studying the hemodynamic effects of titrated subarachnoid anesthesia versus conventional single-shot subarachnoid anesthesia
详细描述
This study aims to investigate whether a different hemodynamic effect is related to the injection o titrated local anesthetic for subarachnoid anesthesia versus the conventional single shot injection. The data to be recorded are blood pressure and pulse rate at different timing. As secondary outcomes the investigators will record the anesthetic level achieved using the Bromage score.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 85 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI 20-40 kg/m2
- •undergoing total hip arthroplasty
- •no controindications to subaracnhoid block
- •able to understand and sign a written informed consensus
- •METs > o = 4
排除标准
- •baseline SBP < 100 mmHg
研究组 & 干预措施
T group
Subaracnhoid block levobupivacaine 0.5%, 10 mg (2 ml) via subarachnoid injection plus 1mg for each metameric level needed to achieve the T10 level sensory block (evaluation with pinprick test at 10 minute after the firts injection and at 4 minute from the second injection)
干预措施: subarachnoid block (Procedure)
S group
levobupivacaine 0.5%, 15 mg (3 ml) via subarachnoid injection
干预措施: subarachnoid block (Procedure)
结局指标
主要结局
SBP change
时间窗: 60 minute
SBP will be recorded at baseline and every 5 minutes after the subarachnoid block for 1 hour
次要结局
未报告次要终点