临床试验/NCT01607203

NCT01607203已完成4 期

Randomised Controlled Trial Comparing hCG Triggering Versus hCG Associated With GnRH Agonist

AZ Jan Palfijn Gent1 个研究点分布在 1 个国家目标入组 120 人开始时间: 2011年11月最近更新: 2015年2月19日

适应症

干预措施

试验速览

阶段: 4 期
状态: 已完成
发起方
入组人数: 120
试验地点: 1
主要终点: MII Oocytes

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to see whether patients triggered with only human Chorion Gonadotropin (hCG) have higher number of Metaphase II oocytes (MII) and implantation rate than patients triggered with hCG combined with Gonadotropin Releasing Hormone (GnRH) agonist.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: None

入排标准

年龄范围: — 至 38 Years（Child, Adult）
性别: Female
接受健康志愿者: 否

入选标准

•Intra-cytoplasmic sperm injection (ICSI) patients below 38 years
•1,2 or 3 rd IVF-cycle

排除标准

•polycystic ovary syndrome (PCOS) patients
•patients with endocrinological diseases or problems

研究组 & 干预措施

hCG

Active Comparator

5000 IU Pregnyl SC

干预措施: pregnyl (Drug)

hCG and GnRH agonist

Active Comparator

5000 IU Pregnyl SC + 0.2 mg Decapeptyl daily SC

干预措施: Decapeptyl Daily (Drug)

hCG and GnRH agonist

Active Comparator

5000 IU Pregnyl SC + 0.2 mg Decapeptyl daily SC

干预措施: pregnyl (Drug)

结局指标

主要结局

MII Oocytes

时间窗: 3 weeks

the number of mature oocytes retrieved

次要结局

Pregnancy Rate(12 weeks)
Patients With Cryopreserved Embryos(4 weeks)

研究者

发起方

AZ Jan Palfijn Gent

申办方类型

Other

责任方

Principal Investigator

主要研究者

Dr. Decleer Wim

gynaecologist

AZ Jan Palfijn Gent

研究点 (1)

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